The brain really can be half asleep, claims research
Moments of absent mindedness such as losing your keys could be the result of tiny parts of the brain taking "naps" to recharge, a study finds.
Researchers discovered that contrary to popular opinion the brain is not always entirely asleep or awake but parts of it can go "offline".
This they claim accounts for the feeling of being "half asleep" which causes forgetfulness and small errors such as misplacing keys or putting the milk in the cupboard or the cereal in the fridge.
The team at the University of Wisconsin, who measured electrical waves in the brain, discovered that some nerve cells in tired yet awake individuals can briefly go "offline".
The study only involved the motor cortex in rats, in other words brain cells to do with movement, but the same processes may hold true for humans, and in many other areas of the brain. This may also be relevant to aspects of hypnotic phenomena, many of which are to do with switching off areas of a brain's functioning for a short time, for example, temporary forgetfulness and catalepsy (physical rigidity and inability to move) and negative hallucination (not seeing things which are there). Hypnosis can produce positive hallucination as well, so obviously there must be other processes at work as well.
Type 2 diabetes 'cut' after weight-loss surgery
http://www.bbc.co.uk/news/health-13052309
"The UK's first large-scale study on the impact of weight-loss surgery has reported a large reduction in type 2 diabetes and other health problems.
A year after surgery, the cases of type 2 diabetes fell by 50%, and on average patients lost nearly 60% of their excess weight, the National Bariatric Surgery Registry said.
It examined the impact of 7,045 operations carried out over two years."
One in ten Britons 'taking pills to get to sleep'
http://www.bbc.co.uk/news/health-12646090
From questioning 40,000 families, which must have been pretty tiring in itself, it appears that one in eight people sleeps less than six hours a night.
Women are more likely to have problems getting to sleep within half an hour than men—24% compared to 18%.
But more men than women said that snoring or coughing disturbs their sleep—30% compared to 20%.
Thirty-three per cent of the most dissatisfied employees reported that they slept poorly, compared to just 18% of the most satisfied employees.
Those who were unemployed were over 40% more likely to have difficulty staying asleep than those in employment.
Not too difficult to take a guess at the reasons for those figures. The slant on the story in The Telegraph is more to do with taking medication to induce sleep. The people they quote point out that taking pills isn't a long-term solution and doesn't induce natural sleep and the attendant health risks in not sleeping enough.
Laughter as medicine?
Laughter as medicine?
I can summarise six articles for you: leg ulcers yes, hospital pain in children yes, blood vessels yes, weight loss yes, asthma no and yes, heart disease possibly, ankylosing spondylitis or maybe reactive arthritis possibly.
Let’s start with asthma. Apparently over half of asthma sufferers in one study report that their asthma is triggered by laughter, but when the asthma is ‘well-controlled’, they can laugh for longer without getting asthma symptoms. I would call that one a draw.
http://news.bbc.co.uk/1/hi/health/4576739.stm
‘Nobody knows how laughter brings on asthma, but it might involve hyperventilating, say the New York University authors.’ Here’s a wild guess: laughter has a spasmodic effect on the chest and diaphragm. Can I have a professorship now, please?
Blood vessels next. Lie down, watch 15 minutes of a funny film or a stress-inducing film, laughter increases blood flow in the brachial artery in your arm by about 22%, stress slows it by about 35%. Now this is interesting, because the bloodstream is a magic sea of nutrients and information and transport.
England 'healthier than the US'
http://www.bbc.co.uk/news/health-12674976
People living in England enjoy better health than Americans, despite less investment in healthcare, research published in the US has revealed.
Across all ages, US residents tend to fare worse in terms of diabetes, high cholesterol and heart disease markers, data on over 100,000 people show.
The reason remains a mystery, says the US team, and challenges the idea that resources necessarily improve health.
It may be due to the UK's bigger drive on disease prevention, they say.
The article goes on to muse about various possible causes, and ask the usual experts what they think. On the face of it, it's a mystery, so some deeper digging was required. The obvious possibilities were obesity and economic factors, but looking at other articles which mention the survey, these were not relevant. The researchers say that the two countries 'share much in terms of history and culture', and another article I saw said that we were basically 'cut from the same cloth'. Ahem. This gave me a starting point. You'll find a slightly more insightful and in-depth description of the research here.
How top anaesthetist's 'fraudulent' claims have put millions of NHS patients at risk
The influential German anaesthetist Joachim Boldt, who possessed a glowing international reputation for his work, is accused of forging various studies which encouraged the use of colloids. Colloids, used to increase blood volume, were thought, based on other studies, to be more dangerous than the alternative, crystalloids, and are certainly vastly more expensive. Boldt received funding from manufacturers of one of the colloids.
I am quoting The Daily Mail version of this for a reason. Amusingly, there are three references in it to quotes given to The Daily Telegraph, so presumably The Mail came to it rather late, although they do have nicer pictures. Which is not difficult since The Telegraph doesn't have any pictures at all. Strangely, The Mail has a quote given to The Telegraph which doesn't even appear in The Telegraph's own article, namely:
Association [of Surgeons] president Prof John MacFie told the Daily Telegraph: 'We have withdrawn the guidelines from our website and we will need to rewrite the article...He drew links with the scandal of Andrew Wakefield who was struck off last year for falsely claiming he had proved that the MMR vaccine and autism were linked. He added: 'What Wakefield did had terrible implications on children's lives, and the principle of this is the same.'
Hypnosis 'eases cancer op pain'
http://news.bbc.co.uk/1/hi/health/6969298.stm
This is infuriating, for reasons I shall explain shortly.
200 women due to receive operations for breast cancer at the Mount Sinai School of Medicine were either given 15 minutes of hypnosis or a conversation with a psychologist before the surgery. The conclusion was that those getting hypnosis required less anaesthetic, and said they had 'less pain, nausea, fatigue and emotional distress' after the operation.
Of course, it's arguable that a conversation with a psychologist just before an operation is precisely what you don't need to reduce pain, nausea, fatigue and emotional distress, and so may have skewed the results, but let's let that one go. The usual stuff about further study being required and 'UK experts said more research was needed' was of course trotted out.
So why is this infuriating? Well, you may have heard of the (world-famous) Mayo Clinic in Minnesota, (though there are now branches in Arizona and Florida as well). The Mayo Clinic became famous for a reason, namely that whereas in most hospitals and clinics 1 in 400 people died from the anaesthetic they were given, patients were sure that wouldn't happen while they were in the hands of the Mayo brothers. They performed 17,000 operations without a single death from anaesthetic. That was because the Mayo brothers had learned to use hypnosis from a doctor called Henry Munro, who had performed numerous operations using hypnosis to reduce the amount of anaesthetic required.
Doctor slang is a dying art
http://news.bbc.co.uk/1/hi/3159813.stm
It's rare that reading a medical article can actually be enjoyable, but this was one of those few occasions where it's at least possible, listing some of the abbreviations doctors use to describe their patients. Apparently the use of these is on the wane due to the increased risk of litigation. Increasingly rare will become phrases like 'pumpkin positive', implying that shining a light into the patient's mouth would have a Halloween effect due its being unimpeded by the patient's miniscule brain.
'DBI refers to "Dirt Bag Index", and multiplies the number of tattoos with the number of missing teeth to give an estimate of the number of days since the patient last bathed.'
I'll let you read the rest for yourself, should you so desire. Doctor Adam Fox, specialist registrar at the Child Allergy Unit in St Mary's hospital, has collected more than 200 examples. His article in Ethics & Behaviour can be downloaded here if you want the serious version. The BMJ's take on it here. And finally a fairly full list here, scroll down to "Terms". You can't say I've left you with nowhere to look further.
Half of all German doctors prescribe placebos, new study shows
http://www.guardian.co.uk/science/2011/mar/06/half-german-doctors-prescribe-placebos?INTCMP=SRCH
This was a study for the German Medical Association, which showed that half of all German doctors, and up to 88% in Bavaria, have prescribed placebos.
'The report says placebos...can prove highly effective in various treatments.'
Christoph Fuchs, the managing director of the BÄK (German Medical Association), says that "Placebos have a stronger impact and are more complex than we realised. They are hugely important in medicine today".
"Placebos can maximise the effect of medication," says Robert Jütte, author of the study and a BÄK board member.
"They can reduce undesirable side-effects and are a more efficient usage of our healthcare budget."
He quoted recent research showing that placebos had proved helpful in 59% of cases of upset stomach, and that they're as effective as antidepressants in about a third of cases. The study also says that placebos are more effective if the patient feels that the doctor understands their concerns and takes them seriously. Laid against this are the ethical dilemmas of prescribing placebos, and so the BÄK are seeking international guidelines.
Hypnosis has 'real' brain effect
http://news.bbc.co.uk/1/hi/health/8359170.stm
This is an article about a Hull University study published in "Consciousness and Cognition" on ten people who were "highly suggestible" and seven who weren't. I had to look around a bit to find more details. Apparently their brains were scanned with an fMRI scanner which is probably not the most neutral environment, a bit like crawling into a tin can and then having elves with hammers beating away on the outside. Not that I've ever had an fMRI. It's just my fantasy version, which is cheaper, of course.
The researchers first tested students for their ability to respond to a range of hypnotic suggestions, including suggestions to see a cat that was not there, to hear non-existent music, and to forget what had happened to them during the hypnotic session. They then invited subjects who could respond to these suggestions, and some that could not, to have their brains examined in an fMRI scanner while under hypnosis. Hypnosis altered anterior brain activity only in those subjects who were able to respond to suggestions. These are the people who may be termed “highly suggestible”.
Cannabis link to increased risk of psychosis
A study published in the BMJ for over 1900 people aged 14-24 at the start of the study, followed up three and eight years later.
'Sir Robin Murray, professor of psychiatric research at the Institute of Psychiatry, said: "This study adds incremental information to the already fairly solid evidence that continued use of cannabis increases risk of psychotic symptoms and psychotic illness. "The study is one of 10 prospective studies all pointing in this same direction." '
I'm not going into the details of the study, but there are two points of interest arising. Firstly, this certainly fits in with my experience as a hypnotherapist. Among the people who come to me with anxiety and phobias, for example, a fair number have used drugs extensively in the past, or else had a bad experience with them. Quite often, though not always, it takes longer working with them to dissolve the emotions than with people without the drugs background.
Ibuprofen may reduce risk of getting Parkinson's disease by a third
http://www.guardian.co.uk/science/2011/mar/02/ibuprofen-parkinsons-disease
"People who take ibuprofen at least twice a week appear to have a 38% lower risk of developing Parkinson's."
So you've now read the headline and the subhead. Now let's look at the reality.
This was from a Boston review of 136,000 patient records of healthworkers, roughly 300 of whom eventually went on to develop Parkinson's disease.
38% Lower than what? 38% lower than people who were taking other painkillers such as aspirin. Excuse me for a moment. I just need to run around whooping with joy and throwing my socks in the air.
Alberto Ascherio, who led the study at Harvard School of Public Health, said the possibility that a readily available, over-the-counter drug could stave off Parkinson's disease was "captivating". Alberto, no offence, but have you thought this through?
This was published in the journal, Neurology. "In an accompanying editorial, James Bower, a neurologist at the Mayo Clinic in Rochester, said the study did not mean people should start taking ibuprofen to protect against Parkinson's, because there are long-term health risks from taking the drug, including a higher risk of intestinal bleeding."
Happiness = Work, sleep and bicycles
http://www.bbc.co.uk/blogs/thereporters/markeaston/2011/02/happiness_work_sleep_and_bicyc.html
The government is trying to find out what makes us happier. I'm delighted the question is at least finally being asked in the UK, this bastion of gloom. Of course, there is plenty of room for cynicism, and there are plenty of people who are willing to provide it. Presumably they fall firmly into the category of people who would benefit from being happier.
According to the article: 'Basically, we have become a whole lot richer but no happier'. My understanding is that unhappiness decreases with wealth up to a certain point but then tails off. If you can't afford a loaf of bread, you're unlikely to be bouncing off the walls with happiness; at the other end of the scale, getting your fifth yacht is unlikely to make you much happier than your fourth did.
The article, which is brief, mentions three areas, as you can probably guess from the title. Unemployment is bad for happiness. No money, no structure to the day, no self-respect, no social interaction, no status. No surprise there.
Alternative remedies 'dangerous' for kids says report
http://www.bbc.co.uk/news/health-12060507
'Alternative remedies can be dangerous for children and even prove fatal if taken instead of conventional drugs, according to a new study...in nearly two thirds of the cases the side effects were rated as severe, life threatening or fatal'.
Before you faint in alarm, let's look at this a little more closely.
'The study, published in the journal Archives of Disease in Childhood, looked at 39 separate incidents reported to the Australian Paediatric Surveillance Unit between 2001 and 2003.'
Already my shock is starting to subside. The BBC are reporting on 39 cases of what is effectively negligence to children, with tragic results, which took place over a two year period in Australia nearly 10 years ago, published in a journal which I didn't know existed, and you probably didn't either, though no doubt it does good work.
So do BBC health correspondents routinely spend their time combing niche Australian medical journals for any nugget of information which may be useful to the British public? Or is it more likely that someone else trying to push a point of view has done it for them?
Fertility treatment success is not prevented by stress
http://www.bbc.co.uk/news/health-12567103
Meta-analysis from Cardiff University reported in the BMJ (British Medical Journal). I can't that say I'm generally exhilarated by meta-analyses, in this case they looked at 14 previous studies and did all the number crunching to conclude that 'stress had no impact on whether a woman became pregnant or not, with women who were stressed becoming pregnant at the same rates as those who did not'.
The first line of the article says that 'The report...aims to dispel the myth that stress prevents women from becoming pregnant.' Actually it doesn't, it merely claims that stress preventing women from becoming pregnant is a myth. Since I can think of at least two examples from my practice in the last year where death of a family member or pet made the woman anovulatory (having no periods) or not far off, I beg to differ. What the report actually shows is that women who complete a cycle of IVF or other 'assisted reproduction techniques' and are more stressed than the others in the same group are equally (un)likely to become pregnant.
The reason loneliness could be bad for your health
http://www.economist.com/node/18226813?story_id=18226813&fsrc=rss
Fascinating article. First of all, according to a meta-analysis of 148 studies from last year, it seems that over the seven and a half year period studied, a gregarious person (someone who likes to be surrounded by other people) has a 50% greater chance of surviving than a lonely person. It's not difficult to find environmental reasons that would explain this: the more people you know, on balance the more people can and will be willing to help you out when you need it, the more popular, happy and consequently healthy you're liable to be, and so on.
What Steven Cole of UCLA has done, however, is to examine the messenger RNA in white blood cells, which tell the genes which proteins to make. It seems that the genes of the lonely were more active in helping to protect against bacteria, (inflammation is an antibacterial response) and the genes of the gregarious were more active in protecting against viruses.
What makes this so interesting is that viruses have to be picked up from someone who's been infected, while bacteria are present in the environment. The implication is that our immunity gets adjusted to the dangers most likely to be presented by a person's usual lifestyle. That's why, according to the conclusions of the above meta-analysis, lonely people tend to have greater susceptibility to heart disease and certain cancers, which are associated with an inflammatory response.
Acupuncture 'more than a placebo'
http://news.bbc.co.uk/1/hi/health/4493011.stm
This was a study done by UCL/University of Southampton jointly, published in the journal NeuroScience, using PET (positron emission tomography) scans to examine brain activity of arthritis sufferers undergoing acupuncture. 14 volunteers each had 3 kinds of treatment in random order: blunt needles, which didn't pierce the skin and which the volunteers realised wouldn't help them, collapsible trick needles which appeared to pierce the skin but didn't, and real acupuncture.
The 3 approaches produced 3 separate patterns of brain activity: the blunt needles just activated the sense of touch; the trick needles stimulated opiate (natural pain-killing activity), and so did the real acupuncture, which also activated a region of the brain known as the insular, thought to be involved in the modulation of pain.
So on the face of it, real acupuncture has a measurable effect on brain activity differing from needles which don't pierce the skin (even if the patient thinks they do). I'm not going into that here, as what interests me is the comment at the bottom of the article from Professor Henry McQuay, professor of pain relief at the University of Oxford: '...it is extremely difficult, technically, to study acupuncture and tease out the placebo effect." That makes perfect sense, as randomised controlled trials are an attempt (among other things) to remove or reduce individual variation in measuring the effectiveness of an outcome.
If homeopathy is just water and sugar pills, why do doctors get so upset about it?/James Delingpole, keeping an open mind on homeopathy
Here are two articles, one by James Delingpole in The Spectator, the other in reply by Tom Chivers in The Daily Telegraph. It has been distasteful to dissect them, as the second comes across as something of an attempted mugging, and I can't pretend to have enjoyed reading it.
Delingpole leads off by introducing his favourite complementary practitioner, Fiona Gross, whose 'daughter broke out in eczema that conventional medicine couldn’t cure. After much reading, research and experimentation, Fiona did cure it, and decided thereafter to make a career of her new-found expertise...'
'she cured a woman...of a mysterious respiratory illness acquired on holiday in Greece. The woman’s GP was flummoxed, as were the various specialists she consulted.'
Stuttering Takes a Star Turn on Screen, and in Research/Unravelling the mystery of faltering speech/Hypnotherapy and Dave Elman
http://www.nytimes.com/2011/02/26/health/26stutter.html
http://www.economist.com/node/18226793
Stuttering is coming under the spotlight at the moment, literally, with the release of the film "The King's Speech" and its possibility of success at the Oscars.
The current focus in science is on brain activity, and a genetic link in half of all stutterers.
“People who stutter have motor difficulties in producing fluent speech,” said Luc De Nil, a speech-language pathologist at the University of Toronto. “They don’t have difficulty developing words or syntax, although they may process language differently. They have difficulty with efficient coordination of motor movements, and speech is such a high-demand fine-motor skill that requires extremely fast sequencing and timing.”
"He has found that parts of the brain linked to the production of speech are more active in stutterers than non-stutterers, while those involved in perceiving sounds are less so. The two sorts of brain look different, too. Stutterers tend, for instance, to have more densely packed grey matter in the areas associated with processing and producing sounds."
Placebo sparks brain painkillers
http://news.bbc.co.uk/1/hi/health/4176078.stm
'US researchers say they have evidence of why some people get pain relief from sham treatment.
They looked at the so-called placebo effect - when a person is successfully treated by a dummy drug just because they believe it works.'
In two succinct paragraphs, the article manages to disparage the amazing human body four times, using the words 'sham', 'dummy', 'placebo' and 'just because they believe it'. This is pretty impressive writing.
The researchers injected salt water into the jaw muscles to cause pain, gave the patients what was supposed to be a pain-killing drug but was actually inert, and found that 9 out of 14 of them (roughly 64% or nearly two thirds) said they had much less pain and could tolerate greater amounts of the salt water. Their endorphin (natural pain-killing) activity increased after they were told they were about to receive the 'pain-killers'.
So the majority of them were able to modulate the amount of pain purely by a thought and a consequent belief. Four areas of the brain were mainly involved: the left dorsolateral prefrontal cortex, the pregenual rostral right anterior cingulate, the right anterior insular cortex and the left nucleus accumbens. There's no nice way I can say that. The activity in the dorsolateral prefrontal cortex was associated with the expectation of relief from pain, the other areas with emotional reactions to it, levels of unpleasantness, and relief from the intensity of pain.
